Multiple mechanisms of germ cell loss in the perinatal mouse ovary

Abstract excerpt

In the perinatal ovary of most mammals, external and internal factors establish a primordial follicle reserve that specifies the duration of the reproductive lifespan of a given species. We analyzed the mechanism of follicle loss and survival in C57BI/6 mice using static and dynamic assays of apoptosis, autophagy, and ovarian morphogenesis. We confirm an initial loss soon after birth, when about 44% of the germ...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Birth, Development, and Health
• Share to Reproductive Biology and Fertility
• Share to Sperm and Testicular Function