Neuronal connectivity as a convergent target of gene × environment interactions that confer risk for Autism Spectrum Disorders.

Abstract excerpt

Evidence implicates environmental factors in the pathogenesis of Autism Spectrum Disorders (ASD). However, the identity of specific environmental chemicals that influence ASD risk, severity or treatment outcome remains elusive. The impact of any given environmental exposure likely varies across a population according to individual genetic substrates, and this increases the difficulty of identifying clear...

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