Article

A role for gene-environment interactions in Autism Spectrum Disorder is suggested by variants in genes regulating exposure to environmental factors

2019-01-15

Abstract excerpt

<h4>Introduction</h4> Autism Spectrum Disorder (ASD) is a clinically heterogeneous neurodevelopmental disorder defined by deficits in social communication and interaction and repetitive and stereotyped interests and behaviors. ASD heritability estimates of 50-83% support a strong role of genetics in its onset, with large sequencing studies reporting a high burden of rare potentially pathogenic copy number variant...

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Literature Corpus work: 5e900f3d-3829-55a4-bc49-c3dfb181db3d
DOI: 10.1101/520544

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