Article
Gene expression in archived newborn blood spots distinguishes infants who will later develop cerebral palsy from matched controls.
Pediatric research - 1 Apr 2013
Ho Nhan Thi, Furge Kyle, Fu Wenjiang, Busik Julia, Khoo Sok Kean, Lu Qing, Lenski Madeleine, Wirth Julia, Hurvitz Edward, Dodge Nancy, Resau James, Paneth Nigel
Abstract excerpt
BACKGROUND: Gene expression in archived newborn blood spots remaining from newborn screening may reflect pathophysiological disturbances useful in understanding the etiology of cerebral palsy (CP). METHODS: We quantified the expression of gene sets representing four physiological pathways hypothesized to contribute to CP in archived unfrozen residual newborn blood spot specimens from 53 children with CP and 53...
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