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Identification of novel biomarkers for neonatal hypoxic-ischemic encephalopathy using iTRAQ

24 May 2020

Abstract excerpt

BACKGROUND: A prompt diagnosis of HIE remains a challenge clinically. This study aimed to identify potential biomarkers of neonatal hypoxic-ischemic encephalopathy (HIE) via a novel proteomic approach, the isobaric tags for absolute and relative quantification (iTRAQ) method. METHODS: Blood samples were collected from neonates with mild (n = 4), moderate (n = 4), or severe (n = 4) HIE who were admitted to the...

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PMID: 32448169
DOI: 10.1186/s13052-020-00822-7

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