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Article

Association between -871C>T promoter polymorphism in the B-cell activating factor gene and the response to rituximab in rheumatoid arthritis patients.

Rheumatology (Oxford, England) - 1 Apr 2013

Ruyssen-Witrand Adeline, Rouanet Stéphanie, Combe Bernard, Dougados Maxime, Le Loët Xavier, Sibilia Jean, Tebib Jacques, Mariette Xavier, Constantin Arnaud

Abstract excerpt

OBJECTIVE: To determine whether a functional single-nucleotide polymorphism in the B-cell activating factor (BAFF) gene correlates with the response to treatment with rituximab (RTX) in RA. METHODS: SMART is a randomized open trial (NCT01126541) assessing two strategies of re-treatment in patients responding to 1-g infusion of RTX with MTX on days 1 and 15 after failure, intolerance or contraindication to TNF...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23264555
DOI: 10.1093/rheumatology/kes344

Genes

TNF
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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