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Article

[Mechanisms of resistance to target therapy].

Nihon rinsho. Japanese journal of clinical medicine - 1 Dec 2012

Matsusaka Satoshi

Abstract excerpt

Cancer therapies are changing from general chemotherapeutic agents to drugs that target specific proteins and signaling pathways. Target therapies, which attack specific cancer cells without harming normal cells, have the potential to treat cancers with fewer side effects than conventional therapies. This article reviews mechanisms of resistance to targeted agents, including genetic resistance, bypass track...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23259396

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