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Article

Effects of an early conformational switch defect during ϕX174 morphogenesis are belatedly manifested late in the assembly pathway.

Journal of virology - 1 Mar 2013

Gordon Emile B, Fane Bentley A

Abstract excerpt

C-terminal, aromatic amino acids in the ϕX174 internal scaffolding protein B mediate conformational switches in the viral coat protein. These switches direct the coat protein through early assembly. In addition to the aromatic amino acids, two acidic residues, D111 and E113, form salt bridges with basic, coat protein side chains. Although salt bridge formation did not appear to be critical for assembly, the...

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Share to Bacteriophage phi X 174
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23255785
DOI: 10.1128/JVI.02839-12
PMCID: PMC3571406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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