Article
The influence of the brain-derived neurotropic factor Val66Met genotype and HMG-CoA reductase inhibitors on insulin resistance in the schizophrenia and bipolar populations.
Clinical and translational science - 1 Dec 2012
Burghardt K J, Pop-Busui R, Bly M J, Grove T B, Taylor S F, Ellingrod V L
Abstract excerpt
INTRODUCTION: The brain-derived neurotrophic factor (BDNF) Val66Met variant and HMG-COA reductase inhibitors (statins) have been implicated in insulin resistance with a possible increased risk of diabetes. We sought to determine the effect of the BDNF Met variant and statin medication use on insulin resistance in schizophrenia and bipolar disorder using the homeostasis model assessment of insulin resistance...
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