Article
Variation in dicer gene is associated with increased survival in T-cell lymphoma.
PloS one - 1 Jan 2012
Li Xi, Tian Xiaobo, Zhang Bo, Zhang Yanqi, Chen Jieping
Abstract excerpt
Dicer, an endonuclease in RNase III family, is essential for the RNA interference (RNAi) pathway. Aberrant expression of Dicer has been shown in various cancers including some subtypes of T cell lymphoma (TCL), which influences patient prognosis. A single-nucleotide polymorphism (SNP) rs3742330A>G has been identified in the Dicer gene, located in the 3' untranslated region (3' UTR) that is important for mRNA...
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