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Article

How the leopard hides its spots: ASIP mutations and melanism in wild cats.

PloS one - 1 Jan 2012

Schneider Alexsandra, David Victor A, Johnson Warren E, O'Brien Stephen J, Barsh Gregory S, Menotti-Raymond Marilyn, Eizirik Eduardo

Abstract excerpt

The occurrence of melanism (darkening of the background coloration) is documented in 13 felid species, in some cases reaching high frequencies at the population level. Recent analyses have indicated that it arose multiple times in the Felidae, with three different species exhibiting unique mutations associated with this trait. The causative mutations in the remaining species have so far not been identified,...

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Source

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Identifiers

PMID: 23251368
DOI: 10.1371/journal.pone.0050386
PMCID: PMC3520955

Genes

ASIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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