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Article

A SINE insertion causes the black-and-tan and saddle tan phenotypes in domestic dogs.

The Journal of heredity - 1 Jan 2000

Dreger Dayna L, Schmutz Sheila M

Abstract excerpt

Agouti Signaling Protein (ASIP) controls the localized expression of red and black pigment in the domestic dog through interaction with other genes, such as Melanocortin 1 Receptor and Beta-Defensin 103. Specific ASIP alleles are necessary for many of the coat color patterns, such as black-and-tan and saddle tan. Mutations in 2 ASIP alleles, a(y) and a, have previously been identified. Here, we characterize a...

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Identifiers

PMID: 21846741
DOI: 10.1093/jhered/esr042

Genes

ASIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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