Article
Association of an Agouti allele with fawn or sable coat color in domestic dogs.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2005
Berryere Tom G, Kerns Julie A, Barsh Gregory S, Schmutz Sheila M
Abstract excerpt
The type of pigment synthesized in mammalian hair, yellow-red pheomelanin or black-brown eumelanin, depends on the interaction between Agouti protein and the Melanocortin 1 receptor. Although the genetics of pigmentation is broadly conserved across most mammalian species, pigment type-switching in domestic dogs is unusual because a yellow-tan coat with variable amounts of dark hair is thought to be caused by an...
Topics
- Agouti Signaling Protein
- Alleles
- Animals
- Base Sequence
- DNA Primers
- Dogs
- Hair
- Intercellular Signaling Peptides and Proteins
- Molecular Sequence Data
- Mutation
- Pedigree
- Pigmentation
- Sequence Analysis, DNA
- Species Specificity