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Molecular Signature of Human amniotic Fluid Stem Cells During Fetal Development

1 Feb 2013

Abstract excerpt

Mid-gestation c-KIT(+) amniotic fluid stem cells (AFSC) have an intermediate phenotype between embryonic and adult stem cells and are easy to reprogram to pluripotency. We previously showed that 1st trimester AFSC can be reprogrammed to functional pluripotency in a transgene-free approach. Despite both parental populations sharing a common phenotype, expressing CD29, CD44, CD73, CD90, CD105, SSEA4 and OCT4, 2nd...

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PMID: 23270629
DOI: 10.2174/1574888x11308010009

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