Article
Sphingolipid synthesis and scavenging in the intracellular apicomplexan parasite, Toxoplasma gondii
16 Dec 2012
Abstract excerpt
Sphingolipids are essential components of eukaryotic cell membranes, particularly the plasma membrane, and are involved in a diverse array of signal transduction pathways. Mammals produce sphingomyelin (SM) as the primary complex sphingolipid via the well characterised SM synthase. In contrast yeast, plants and some protozoa utilise an evolutionarily related inositol phosphorylceramide (IPC) synthase to...
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