Article
Impact of tobacco on glutathione S transferase gene loci of Indian ethnics.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Senthilkumar K P, Thirumurugan Ramasamy
Abstract excerpt
BACKGROUND: Tobacco contains agents which generate various potent DNA adducts that can cause gene mutations. Production of DNA adducts may be neutralized by glutathione S transferase (GST) along with other phase I and phase II enzyme systems. The existence of null type of GST among the population increases the susceptibility to various disorders and diseases. The present study focuses on the impact of high...
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