Article
Telomere length in mantle cell lymphoma.
Blood - 14 Feb 2013
Jebaraj Billy Michael Chelliah, Kienle Dirk, Lechel André, Mertens Daniel, Heuberger Maria, Ott German, Rosenwald Andreas, Barth Thomas F E, Möller Peter, Zenz Thorsten, Döhner Hartmut, Stilgenbauer Stephan
Abstract excerpt
Telomere shortening is of pathogenic and prognostic importance in cancers. In the present study, we analyzed telomere length in 73 mantle cell lymphoma (MCL), 55 chronic lymphocytic leukemia (CLL), and 20 normal B-cell samples using quantitative PCR (Q-PCR) to study its association with disease characteristics and outcome. Telomere length was found to be highly variable in MCL (range, 2.2-13.8 kb; median, 4.3...
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