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To<i>BRAF</i>or Not to<i>BRAF</i>: Is That Even a Question Anymore?

14 Dec 2012

Abstract excerpt

Alterations in BRAF have been discovered in most pediatric low-grade gliomas. Because the field has moved quickly during the past few years, there is not yet widespread awareness about what B-Raf normally does, how the BRAF gene is modified in gliomas, why mutant proteins promote gliomagenesis, and what an abnormal BRAF result means for diagnosis, prognosis, and treatment. Depending on the data from ongoing...

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PMID: 23242278
DOI: 10.1097/nen.0b013e318279f3db

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