Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microarray with LNA-probes for genotyping of polymorphic variants of Gilbert's syndrome gene UGT1A1(TA)n.

Clinical chemistry and laboratory medicine - 1 Jun 2013

Fesenko Eugeny E, Heydarov Rustam N, Stepanova Eugenia V, Abramov Michael E, Chudinov Alexander V, Zasedatelev Alexander S, Mikhailovich Vladimir M

Abstract excerpt

BACKGROUND: Gilbert's syndrome is a common metabolic dysfunction characterized by elevated levels of unconjugated bilirubin in the bloodstream. This condition is usually caused by additional (TA) insertions in a promoter region of the uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) gene, which instead of the sequence А(TА)6TАА contains А(TА)7TАА. While the condition itself is benign, it presents elevated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Gilbert Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucuronosyltransferase

Share to Neoplasms

Share to Oligonucleotide Array Sequence Analysis

Share to Oligonucleotides

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 23241680
DOI: 10.1515/cclm-2012-0656

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microarray with LNA-probes for genotyping of polymorphic variants of Gilbert's syndrome gene UGT1A1(TA)n.PMID 23241680Read ↗

Three-dimensional polyacrylamide gel-based DNA microarray method effectively identifies UDP-glucuronosyltransferase 1A1 gene polymorphisms for the correct diagnosis of Gilbert's syndrome.Semantic proximity Read ↗

Single-step identification of all length polymorphisms in the UGT1A1 gene promoter.Semantic proximity Read ↗

DNA base bulge vs unmatched end formation in probe-based diagnostic insertion/deletion genotyping: genotyping the UGT1A1 (TA)(n) polymorphism by real-time fluorescence PCR.Semantic proximity Read ↗

Rapid screening of 12 common mutations in Turkish GSD 1a patients using electronic DNA microarray.Semantic proximity Read ↗

Rapid and sensitive detection of UGT1A1 polymorphisms associated with irinotecan toxicity by a novel DNA microarray.Semantic proximity Read ↗

Gilbert’s syndrome: High frequency of the (TA)7TAA allele in India and its interaction with a novel CAT insertion in promoter of the gene for bilirubin UDP-glucuronosyltransferase 1 geneSemantic proximity Read ↗

UGT1A1(TA)n promoter polymorphism--a new case of a (TA)8 allele in Caucasians.Semantic proximity Read ↗

Electronic microarray technique for detection of nine base substitutions including single-nucleotide polymorphisms in the human OGG1 gene.Semantic proximity Read ↗

High-throughput single-base mismatch detection for genotyping of UDP-glucuronosyltransferase (UGT1A1) with probe capture assay coupled with modified allele-specific primer extension reaction (MASPER).Semantic proximity Read ↗

Single nucleotide polymorphism genotyping using locked nucleic acid (LNA).Semantic proximity Read ↗

Rapid detection of glycogen storage disease type Ia by DNA microarray.Semantic proximity Read ↗

TaqMan real time PCR for the Detection of the Gilbert's Syndrome Markers UGT1A1*28; UGT1A1*36 and UGT1A1*37.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.