Article
A hormone receptor-based transactivator bridges different binary systems to precisely control spatial-temporal gene expression in Drosophila.
PloS one - 1 Jan 2012
Kuo Shu-Yun, Tu Chiao-Hui, Hsu Ya-Ting, Wang Horng-Dar, Wen Rong-Kun, Lin Chen-Ta, Wu Chia-Lin, Huang Yu-Ting, Huang Guan-Shieng, Lan Tsuo-Hung, Fu Tsai-Feng
Abstract excerpt
The GAL4/UAS gene expression system is a precise means of targeted gene expression employed to study biological phenomena in Drosophila. A modified GAL4/UAS system can be conditionally regulated using a temporal and regional gene expression targeting (TARGET) system that responds to heat shock induction. However heat shock-related temperature shifts sometimes cause unexpected physiological responses that confound...
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