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Article

Accumulation of slightly deleterious mutations in the mitochondrial genome: a hallmark of animal domestication.

Gene - 15 Feb 2013

Hughes Austin L

Abstract excerpt

The hypothesis that domestication leads to a relaxation of purifying selection on mitochondrial (mt) genomes was tested by comparative analysis of mt genes from dog, pig, chicken, and silkworm. The three vertebrate species showed mt genome phylogenies in which domestic and wild isolates were intermingled, whereas the domestic silkworm (Bombyx mori) formed a distinct cluster nested within its closest wild relative...

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Identifiers

PMID: 23237775
DOI: 10.1016/j.gene.2012.11.064
PMCID: PMC3895481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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