Article
Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium.
PloS one - 1 Jan 2012
Schurmann Claudia, Heim Katharina, Schillert Arne, Blankenberg Stefan, Carstensen Maren, Dörr Marcus, Endlich Karlhans, Felix Stephan B, Gieger Christian, Grallert Harald, Herder Christian, Hoffmann Wolfgang, Homuth Georg, Illig Thomas, Kruppa Jochen, Meitinger Thomas, Müller Christian, Nauck Matthias, Peters Annette, Rettig Rainer, Roden Michael, Strauch Konstantin, Völker Uwe, Völzke Henry, Wahl Simone, Wallaschofski Henri, Wild Philipp S, Zeller Tanja, Teumer Alexander, Prokisch Holger, Ziegler Andreas
Abstract excerpt
Microarray profiling of gene expression is widely applied in molecular biology and functional genomics. Experimental and technical variations make meta-analysis of different studies challenging. In a total of 3358 samples, all from German population-based cohorts, we investigated the effect of data preprocessing and the variability due to sample processing in whole blood cell and blood monocyte gene expression...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.