Article
SPP1 gene polymorphisms associated with nephrolithiasis in Turkish pediatric patients.
Urology journal - 1 Jan 2012
Tekin Gökhan, Ertan Pelin, Horasan Gönül, Berdeli Afig
Abstract excerpt
PURPOSE: To investigate the association between SPP1 gene polymorphisms and nephrolithiasis. MATERIALS AND METHODS: A total of 65 pediatric patients and 50 healthy controls were enrolled in this study. Two known polymorphisms of the SPP1 gene, c.240T > C and c.708C > T nucleotide substitutions, both of which were also known as synonymous aminoacid polymorphisms, D80D and A236A, respectively, at SPP1 gene cDNA...
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