Article
[Association between single nucleotide polymorphisms in -88 and -123 loci of MxA gene promoter region and HCV susceptibility and IFN-α efficacy].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology - 1 Dec 2012
Hu Chun-hui, Chen Jin, Yang Rui, Li Nan-nan, Yang Bo, Ma Dan, Liang Xiao-cui, Wang Qun
Abstract excerpt
AIM: To investigate the association between the single nucleotide polymorphisms(SNP) in -88 and -123 loci of myxovirus resistance 1(MxA) gene promoter region and the susceptibility to heptaitis C virus(HCV) in Han Chinese, and evaluate the relationship between all of the genotypes and the treatment response to IFN-α. METHODS: Genotypes of -88(G/T) and -123(C/A) loci of the MxA promoter were examined by the...
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