Protein kinase profiling in miscarriage: implications for the pathogenesis of trisomic pregnancy.

Abstract excerpt

OBJECTIVE: Trisomy in pregnancy increases risks of miscarriage, fetal anomalies, and perinatal complications, with trisomy 16 the most common trisomy in human conceptions. The pathogenesis and protein expression profiles in trisomic pregnancy have not been well elucidated. Our objective was to profile protein kinase expression in trisomic and chromosomally normal miscarriage. METHODS: Placental chorionic villus...

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