Article
[Role of methyltetrahydrofolate reductase (MTHFR) gene polymorphism in the development of ischemic stroke in the dwellers of the Kyrgyz Republic].
Terapevticheskii arkhiv - 1 Jan 2012
Kudaĭbergenova N T, Moldotashev I K, Aldashev A A, Mukhanova A K
Abstract excerpt
AIM: To study the role of MTHFR gene polymorphism in patients with ischemic stroke (IS) in the Kyrgyz Republic. SUBJECTS AND METHODS: Molecular genetic testing of C677T polymorphism in the MTHFR gene was carried out in 107 Kyrgyz patients with prior IS. The patients were grouped according to the severity of motor impairments and the level of blood pressure (BP). The MTHFR C677T polymorphism was genotyped by...
Topics
- Blood Pressure
- Brain Ischemia
- Genetic Predisposition to Disease
- Genetic Testing
- Genotype
- Humans
- Kyrgyzstan
- Methylenetetrahydrofolate Reductase (NADPH2)
- Mutation
- Polymorphism, Genetic
