Article
[Polymorphisms of ACE-1 and MTHFR genes and genetic susceptibility of ischemic stroke].
Zhonghua yi xue za zhi - 10 Aug 2002
Li Caiming, Zhang Cheng, Qiu Shulian, Lu Xilin, Zeng Ying, Wu Haixin, Chen Weiqi, Luo Weiliang, Liu Jihong
Abstract excerpt
OBJECTIVE: To study the relationships between polymorphisms of angiotensin-converting enzyme 1 (ACE-1) gene and N(5),N(10) -methylene-tetra-hydrofolic acid reductase (MTHFR) gene and ischemic stroke (IS). METHODS: The polymorphisms of ACE-1 and MTHFR genes in the peripheral white blood cells of 143 patients with IS and 154 controls were analyzed using PCR- RFLP. RESULTS: The frequencies of II, ID, and DD...
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