Article
Mouse eye enucleation for remote high-throughput phenotyping.
Journal of visualized experiments : JoVE - 19 Nov 2011
Mahajan Vinit B, Skeie Jessica M, Assefnia Amir H, Mahajan Maryann, Tsang Stephen H
Abstract excerpt
The mouse eye is an important genetic model for the translational study of human ophthalmic disease. Blinding diseases in humans, such as macular degeneration, photoreceptor degeneration, cataract, glaucoma, retinoblastoma, and diabetic retinopathy have been recapitulated in transgenic mice.(1-5) Most transgenic and knockout mice have been generated by laboratories to study non-ophthalmic diseases, but genetic...
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