Comparison of simple and modified Bernstein's methods in estimation of recessive allele frequency in the HLA system.

doi:10.1111/j.1469-1809.1990.tb00362.x

Back to search

Article

Comparison of simple and modified Bernstein's methods in estimation of recessive allele frequency in the HLA system.

Annals of human genetics - 1 Jan 1990

Nam J M

Abstract excerpt

Bias and inefficiency of Bernstein's estimator of the recessive allele frequency in generalized ABO-like systems are important for situations where the frequency is small and the number of codominant alleles is large. A modified Bernstein's estimator of the recessive (Smith, 1967) has much smalle...

Topics

ABO Blood-Group System
Alleles
Gene Frequency
Genes, Recessive
HLA Antigens
Humans
Methods

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.