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Article

5-HTTLPR and early childhood adversities moderate cognitive and emotional processing in adolescence.

PloS one - 1 Jan 2012

Owens Matthew, Goodyer Ian M, Wilkinson Paul, Bhardwaj Anupam, Abbott Rosemary, Croudace Tim, Dunn Valerie, Jones Peter B, Walsh Nicholas D, Ban Maria, Sahakian Barbara J

Abstract excerpt

BACKGROUND: Polymorphisms in the promoter region of the serotonin transporter gene (5-HTTLPR) and exposure to early childhood adversities (CA) are independently associated with individual differences in cognitive and emotional processing. Whether these two factors interact to influence cognitive and emotional processing is not known. METHODOLOGY AND PRINCIPAL FINDINGS: We used a sample of 238 adolescents from a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23209555
DOI: 10.1371/journal.pone.0048482
PMCID: PMC3509124

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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