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Article

Duodenal Neoplasms of Gastric Phenotype: An Immunohistochemical and Genetic Study With a Practical Approach to the Classification.

The American journal of surgical pathology - 1 Mar 2017

Hida Risa, Yamamoto Hidetaka, Hirahashi Minako, Kumagai Reiko, Nishiyama Kenichi, Gi Toshihiro, Esaki Motohiro, Kitazono Takanari, Oda Yoshinao

Abstract excerpt

Duodenal neoplasm of gastric phenotype (DNGP) is very rare, and details of its histopathologic, genetic, and biological features are still unclear. Frequent gene mutations in GNAS, KRAS, and APC have been reported in pyloric gland adenomas and fundic gland-type neoplasms (initially reported as low-grade adenocarcinomas) of the stomach. Here we retrospectively analyzed 16 cases of extra-ampullary DNGP (benign to...

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Source

Identifiers

PMID: 27984236
DOI: 10.1097/PAS.0000000000000785

Genes

APC
GNAS
KRAS
BRAF
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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