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Article

Identification of novel E6-E7 sequence variants of human papillomavirus 16.

Archives of virology - 1 Apr 2013

Tsakogiannis D, Kyriakopoulou Z, Amoutzias G, Ruether I G A, Dimitriou T G, Panotopoulou E, Markoulatos P

Abstract excerpt

The rate of evolution of the human papillomavirus 16 (HPV16) genome is low. However, the ability of the E6 oncoprotein to interact with distinct p53 variants causes selective pressure on the E6 gene. In addition, intratypic recombination events in the HPV16 E6 and E7 genes have been characterized as extraordinary phenomena during the evolutionary history of virus. In the present study, we identified two new...

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PMID: 23208280
DOI: 10.1007/s00705-012-1555-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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