Article
Kras mutations and p53 overexpression in pseudomyxoma peritonei: association with phenotype and prognosis.
The Journal of surgical research - 1 Mar 2013
Shetty Shreya, Thomas Peter, Ramanan Bala, Sharma Poonam, Govindarajan Venkatesh, Loggie Brian
Abstract excerpt
BACKGROUND: Little information exists on Kras mutations and p53 overexpression in pseudomyxoma peritonei (PMP). These genetic alterations are associated with poorer prognoses in colorectal cancer. We postulated that these mutations might be more frequent in high-grade (HG) PMP (peritoneal mucinou...
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