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Article

Drosophila interspecific hybrids phenocopy piRNA-pathway mutants.

PLoS biology - 1 Jan 2012

Kelleher Erin S, Edelman Nathaniel B, Barbash Daniel A

Abstract excerpt

The Piwi-interacting RNA (piRNA) pathway defends the germline of animals from the deleterious activity of selfish transposable elements (TEs) through small-RNA mediated silencing. Adaptation to novel invasive TEs is proposed to occur by incorporating their sequences into the piRNA pool that females produce and deposit into their eggs, which then propagates immunity against specific TEs to future generations. In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23189033
DOI: 10.1371/journal.pbio.1001428
PMCID: PMC3506263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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