Article
Allele specific expression of the transthyretin gene in swedish patients with hereditary transthyretin amyloidosis (ATTR V30M) is similar between the two alleles.
PloS one - 1 Jan 2012
Norgren Nina, Hellman Urban, Ericzon Bo Göran, Olsson Malin, Suhr Ole B
Abstract excerpt
BACKGROUND: Hereditary transthyretin (TTR) amyloidosis (ATTR) is an autosomal dominant disease characterized by extracellular deposits of amyloid fibrils composed of misfolded TTR. The differences in penetrance and age at onset are vast, both between and within populations, with a generally late onset for Swedish carriers. In a recent study the entire TTR gene including the 3' UTR in Swedish, French and Japanese...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.