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Article

Genetic and Clinical Spectrum of Hereditary Transthyretin Amyloidosis in Brazil.

Journal of the peripheral nervous system : JPNS - 1 Mar 2026

Maximiano-Alves Gustavo, Lavigne-Moreira Carolina, Simões Marcus Vinicius, Galvão Adilson Junior Pinto, Valicelli Flavio Henrique, Coneglian Fernando Saraiva, Vegezzi Elisa, Garibaldi Pedro Manoel Marques, Tomaselli Pedro José, Cortese Andrea, Marques Wilson

Abstract excerpt

BACKGROUND: Transthyretin hereditary amyloidosis (ATTRv) clinical variability has been widely reported, not only across countries and variants but also among families and distinct regions within a single nation. One of the principal challenges in disease management is the accurate determination of age of onset (AOO), which is heterogeneous and has therapeutic implications given the availability of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41498649
DOI: 10.1111/jns.70097
PMCID: PMC12777902

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TTR

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