Article
Rhodopsin gene expression determines rod outer segment size and rod cell resistance to a dominant-negative neurodegeneration mutant.
PloS one - 1 Jan 2012
Price Brandee A, Sandoval Ivette M, Chan Fung, Nichols Ralph, Roman-Sanchez Ramon, Wensel Theodore G, Wilson John H
Abstract excerpt
Two outstanding unknowns in the biology of photoreceptors are the molecular determinants of cell size, which is remarkably uniform among mammalian species, and the mechanisms of rod cell death associated with inherited neurodegenerative blinding diseases such as retinitis pigmentosa. We have addr...
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