Article
Enteropeptidase: a gene associated with a starvation human phenotype and a novel target for obesity treatment.
PloS one - 1 Jan 2012
Braud Sandrine, Ciufolini Marco A, Harosh Itzik
Abstract excerpt
BACKGROUND: Obesity research focuses essentially on gene targets associated with the obese phenotype. None of these targets have yet provided a viable drug therapy. Focusing instead on genes that are involved in energy absorption and that are associated with a "human starvation phenotype", we have identified enteropeptidase (EP), a gene associated with congenital enteropeptidase deficiency, as a novel target for...
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