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Article

Alterations in the Ure2 αCap domain elicit different GATA factor responses to rapamycin treatment and nitrogen limitation.

The Journal of biological chemistry - 18 Jan 2013

Feller Andre, Georis Isabelle, Tate Jennifer J, Cooper Terrance G, Dubois Evelyne

Abstract excerpt

Ure2 is a phosphoprotein and central negative regulator of nitrogen-responsive Gln3/Gat1 localization and their ability to activate transcription. This negative regulation is achieved by the formation of Ure2-Gln3 and -Gat1 complexes that are thought to sequester these GATA factors in the cytoplasm of cells cultured in excess nitrogen. Ure2 itself is a dimer the monomer of which consists of two core domains and a...

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Identifiers

PMID: 23184930
DOI: 10.1074/jbc.M112.385054
PMCID: PMC3548494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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