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Article

Ceramide stress in survival versus lethal autophagy paradox

26 Nov 2012

Abstract excerpt

In a recent study, characterization of novel mechanisms that regulate lethal autophagy revealed that C 18-ceramide stress mediates LC3B-II-ceramide binding on mitochondrial membranes to target autophagosomes for mitophagy induction and tumor suppression.

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Identifiers

PMID: 23182807
DOI: 10.4161/auto.22739

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