Article
Antineutrophil cytoplasmic autoantibody-associated vasculitis in Chinese patients.
Clinical and experimental nephrology - 1 Oct 2013
Xu Peng-Cheng, Chen Min, Zhao Ming-Hui
Abstract excerpt
Antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) is a common autoimmune disease in China. AAVs in the majority of Chinese patients are microscopic polyangiitis with antigenicity to myeloperoxidase. Propylthiouracil is the leading cause of drug-induced AAV. The genetic background and immunological characteristics of ANCA, such as the epitope, IgG subclass and avidity, might contribute to...
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