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Article

A depressive phenotype induced by Bacille Calmette Guérin in 'susceptible' animals: sensitivity to antidepressants.

Psychopharmacology - 1 Apr 2013

Platt Brian, Schulenberg Janet, Klee Nicole, Nizami Maryam, Clark Janet A

Abstract excerpt

RATIONALE: The depressive phenotype in the BCG model of chronic inflammation has not been pharmacologically characterized. OBJECTIVES: This study aims to characterize the BCG model and establish its pharmacological sensitivity to fluoxetine, desipramine, and diazepam. MATERIALS AND METHODS: CD-1 mice were dosed with Bacille Calmette-Guérin (BCG) and measures of body weight, locomotor activity, and immobility in...

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PMID: 23179968
DOI: 10.1007/s00213-012-2923-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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