Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Anti-tumour activity of two novel compounds in cisplatin-resistant testicular germ cell cancer

1 Nov 2012

Abstract excerpt

BACKGROUND: Resistance to cisplatin-based chemotherapy is associated with poor prognosis in testicular germ cell cancer, emphasising the need for new therapeutic approaches. In this respect, the therapeutic concept of anti-angiogenesis is of particular interest. In a previous study, we presented two novel anti-angiogenic compounds, HP-2 and HP-14, blocking the tyrosine kinase activity of angiogenic growth factor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Sperm and Testicular Function
Share to Testicular diseases and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23169338
DOI: 10.1038/bjc.2012.481

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Anti-tumour activity of two novel compounds in cisplatin-resistant testicular germ cell cancerPMID 23169338Read ↗

Cisplatin Resistance in Testicular Germ Cell Tumors: Current Challenges from Various PerspectivesSemantic proximity Read ↗

Differential gene expression in cisplatin-resistant and -sensitive testicular germ cell tumor cell linesSemantic proximity Read ↗

Molecular Mechanisms of Cisplatin Chemoresistance and Its Circumventing in Testicular Germ Cell TumorsSemantic proximity Read ↗

Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profilesSemantic proximity Read ↗

Testicular Germ Cell Tumors Acquire Cisplatin Resistance by Rebalancing the Usage of DNA Repair PathwaysSemantic proximity Read ↗

Cisplatin resistance in germ cell tumours: models and mechanismsSemantic proximity Read ↗

Mirvetuximab Soravtansine Induces Potent Cytotoxicity and Bystander Effect in Cisplatin-Resistant Germ Cell Tumor CellsSemantic proximity Read ↗

Therapeutic potential of Mdm2 inhibition in malignant germ cell tumours.Semantic proximity Read ↗

Revisiting DNA damage repair, p53-mediated apoptosis and cisplatin sensitivity in germ cell tumorsSemantic proximity Read ↗

Cisplatin-induced apoptosis in human malignant testicular germ cell lines depends on MEK/ERK activationSemantic proximity Read ↗

Micro-RNA expression in cisplatin resistant germ cell tumor cell linesSemantic proximity Read ↗

Targeting of Deregulated Wnt/β-Catenin Signaling by PRI-724 and LGK974 Inhibitors in Germ Cell Tumor Cell LinesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.