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Prognostic relevance and therapeutic implications of centromere protein F expression in patients with esophageal squamous cell carcinoma

16 Nov 2012

Abstract excerpt

Centromere protein F (CENP-F), a cell cycle-regulated centromere protein, has been shown to affect numerous tumorigenic processes. This study aimed to clarify the prognostic significance of CENP-F expression in patients with esophageal squamous cell carcinoma (ESCC). The levels of CENP-F messenger RNA and protein were higher in ESCC cell lines than in the normal tissues. An immunohistochemical analysis of paired...

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PMID: 23163484
DOI: 10.1111/dote.12002

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