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Article

Definitive endoderm derived from human embryonic stem cells highly express the integrin receptors αV and β5

1 Jan 2010

Abstract excerpt

Human embryonic stem cells (hESCs) can be directed to differentiate into a number of endoderm cell types, however mature functional cells have yet to be produced in vitro. This suggests that there may be important factors that have yet to be described, which may be essential for the proper derivation of these cells. One such factor is the integrin mediated interactions between a cell and the extracellular matrix...

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PMID: 20026907
DOI: 10.4161/cam.4.1.10627

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