Article
Diamine oxidase rs10156191 and rs2052129 variants are associated with the risk for migraine.
Headache - 1 Feb 2015
García-Martín Elena, Martínez Carmen, Serrador Mercedes, Alonso-Navarro Hortensia, Ayuso Pedro, Navacerrada Francisco, Agúndez José A G, Jiménez-Jiménez Félix Javier
Abstract excerpt
BACKGROUND: Histamine has been implicated in the pathogenesis of migraine. We investigated the possible association between functional single nucleotide polymorphisms (SNPs) in the diamine oxidase gene (DAO; chromosome 7q36.1, involved in histamine metabolism) and the risk for migraine. METHODS: We studied the frequency of the rs2052129, rs10156191, rs1049742, and rs1049793 genotypes and allelic variants in 197...
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