Article
Folate in pregnancy and imprinted gene and repeat element methylation in the offspring.
The American journal of clinical nutrition - 1 Jan 2013
Haggarty Paul, Hoad Gwen, Campbell Doris M, Horgan Graham W, Piyathilake Chandrika, McNeill Geraldine
Abstract excerpt
BACKGROUND: Epigenetic regulation of imprinted genes and transposable elements has been implicated in human disease and may be affected by maternal diet. OBJECTIVE: The objective was to determine the effect on offspring epigenetic status of nutritional and genetic factors that influence folate exposure in pregnancy. DESIGN: We measured folate intake from diet, the use of folic acid supplements and the period of...
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