Article
Detection and differential diagnosis of colon cancer by a cumulative analysis of promoter methylation.
Nature communications - 1 Jan 2012
Yang Qiong, Dong Ying, Wu Wei, Zhu Chunlei, Chong Hui, Lu Jiangyang, Yu Dehai, Liu Libing, Lv Fengting, Wang Shu
Abstract excerpt
Alterations in the methylation of promoters of cancer-related genes are promising biomarkers for the early detection of disease. Compared with single methylation alteration, assessing combined methylation alterations can provide higher association with specific cancer. Here we use cationic conjugated polymer-based fluorescence resonance energy transfer to quantitatively analyse DNA methylation levels of seven...
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