Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MTHFR C677T polymorphism modifies the effect of HRT on metabolic parameters in postmenopausal women.

Climacteric : the journal of the International Menopause Society - 1 Oct 2013

Lambrinoudaki I, Papadimitriou D, Kaparos G, Rizos D, Panoulis C, Deligeoroglou E, Alexandrou A, Auguolea A, Apostolakis M, Creatsa M, Kouskouni E

Abstract excerpt

OBJECTIVE: To assess the interaction of the MTHFR C677T polymorphism with changes in lipid and glucose metabolism effected by oral hormone replacement therapy (HRT) in postmenopausal women. METHODS: In this open-label, prospective, interventional study, parameters of lipid and glucose metabolism, as well as homocysteine, were assessed in 97 postmenopausal women at baseline and 1 year after the initiation of HRT....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Glucose
Share to Cholesterol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol, LDL

Share to Estrogen Replacement Therapy

Share to Homocysteine

Share to Lipid Metabolism

Share to Postmenopause

Share to Triglycerides

Source

Identifiers

PMID: 23145891
DOI: 10.3109/13697137.2012.738722

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MTHFR C677T polymorphism modifies the effect of HRT on metabolic parameters in postmenopausal women.PMID 23145891Read ↗

ESR1 and APOE gene polymorphisms, serum lipids, and hormonal replacement therapy.Semantic proximity Read ↗

Effect of oral hormone replacement therapy on plasma homocysteine levels.Semantic proximity Read ↗

The C677T methylenetetrahydrofolate reductase polymorphism influences the homocysteine-lowering effect of hormone replacement therapy.Semantic proximity Read ↗

Effect of interaction between adherence to a Mediterranean diet and the methylenetetrahydrofolate reductase 677C-->T mutation on homocysteine concentrations in healthy adults: the ATTICA Study.Semantic proximity Read ↗

CYP A-204C polymorphism is associated with subclinical atherosclerosis in postmenopausal women.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase 677 C/T genotype and cardiovascular disease mortality in postmenopausal women.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T polymorphism is associated with central adiposity and increased androgenicity in healthy postmenopausal women.Semantic proximity Read ↗

MTHFR C677T polymorphism and osteoporotic fracture in postmenopausal women: a meta-analysis.Semantic proximity Read ↗

Effect of lifestyle factors on plasma total homocysteine concentrations in relation to MTHFR(C677T) genotype. Inter99 (7).Semantic proximity Read ↗

Is there an association between the development of metabolic syndrome in PCOS patients and the C677T MTHFR gene polymorphism?Semantic proximity Read ↗

Effect of hormone replacement therapy on plasma lipoproteins and apolipoproteins, endothelial function and myocardial perfusion in postmenopausal women with estrogen receptor-alpha IVS1-397 C/C genotype and established coronary artery disease.Semantic proximity Read ↗

Changes in lifestyle and total homocysteine in relation to MTHFR(C677T) genotype: the Inter99 study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.