Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Celsr1-3 cadherins in PCP and brain development.

Current topics in developmental biology - 1 Jan 2012

Boutin Camille, Goffinet André M, Tissir Fadel

Abstract excerpt

Cadherin EGF LAG seven-pass G-type receptors 1, 2, and 3 (Celsr1-3) form a family of three atypical cadherins with multiple functions in epithelia and in the nervous system. During the past decade, evidence has accumulated for important and distinct roles of Celsr1-3 in planar cell polarity (PCP) and brain development and maintenance. Although the role of Celsr in PCP is conserved from flies to mammals, other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cadherins
Share to Cell Movement
Share to Cell Polarity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hair Follicle

Share to Neurons

Share to Receptors, Cell Surface

Share to Receptors, G-Protein-Coupled

Source

Identifiers

PMID: 23140629
DOI: 10.1016/B978-0-12-394592-1.00010-7

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Celsr1-3 cadherins in PCP and brain development.PMID 23140629Read ↗

Understanding cadherin EGF LAG seven‐pass G‐type receptorsSemantic proximity Read ↗

The planar cell polarity Vangl2 protein: From genetics to cellular and molecular functions.Semantic proximity Read ↗

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.Semantic proximity Read ↗

Protocadherin Celsr3 is crucial in axonal tract development.Semantic proximity Read ↗

The role of G protein-coupled receptors in cochlear planar cell polarity.Semantic proximity Read ↗

The Planar Cell Polarity Pathway Drives Pathogenesis of Chronic Lymphocytic Leukemia by the Regulation of B-Lymphocyte MigrationSemantic proximity Read ↗

Genetic evidence in planar cell polarity signaling pathway in human neural tube defects.Semantic proximity Read ↗

Systematic expression analysis of the CELSR family reveals the importance of CELSR3 in human lung adenocarcinomaSemantic proximity Read ↗

Planar cell polarity in Drosophila.Semantic proximity Read ↗

Cadherins in neuronal morphogenesis and function.Semantic proximity Read ↗

CELSR2, encoding a planar cell polarity protein, is a putative gene in Joubert syndrome with cortical heterotopia, microophthalmia, and growth hormone deficiency.Semantic proximity Read ↗

Genetic evidence that Celsr3 and Celsr2, together with Fzd3, regulate forebrain wiring in a Vangl-independent manner.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.